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Halozyme withdraws €2B Evotec acquisition proposal

Halozyme Therapeutics said Friday that it has pulled its proposal to buy Evotec, a struggling German biotech that Halozyme said was "unwilling to engage" in deal talks. Last week, San Diego ...

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From vaccines to psychedelics, five drugmakers on what could change under a...

President-elect Donald Trump and Robert Kennedy, Jr. — his pick to head up the Department of Health and Human Services — were hot topics at the Jefferies London Healthcare Conference this week as...

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Senate committee advances pharma patent challenge bill

The Senate Judiciary Committee narrowly advanced a bill Thursday that would change the way the Patent Trial and Appeal Board operates, limiting the ability of parties to challenge patents in court and...

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Drug or biologic? An Eli Lilly lawsuit could impact weight loss drug compounders

Eli Lilly and Novo Nordisk have filed dozens of lawsuits against compounding pharmacies marketing their own versions of popular weight loss and diabetes drugs. A new legal strategy could put Lilly one...

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Sanofi introduces new 340B payment model — report

Sanofi is proposing a new model for distributing drug discounts under the federal 340B program, according to the Wall Street Journal, in an effort that is almost certain to create pushback ...

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FDA approves BridgeBio's heart disease drug, setting up competition with...

The FDA approved BridgeBio’s ​​acoramidis in a rare, genetic heart disease that’s expected to become an intense area of market competition, and a broad label will give it a near-immediate boost against...

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Trump picks Johns Hopkins researcher Marty Makary to lead the FDA

President-elect Donald Trump selected Marty Makary to lead the FDA, choosing a Johns Hopkins University surgeon who has called the US government the “greatest perpetrator of misinformation during the...

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Trump picks former congressman and vaccine injury advocate to lead CDC

Physician, veteran and former Florida Congressman Dave Weldon is President-elect Donald Trump’s pick to lead the CDC, giving Robert F. Kennedy Jr. a key ally in his planned review of the safety of...

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Trump announces picks for FDA, CDC; Novartis seeks bolt-on deals, raises...

Welcome back to Endpoints Weekly, your review of the week’s top biopharma headlines. Want this in your inbox every Saturday morning? Current Endpoints readers can visit their reader profile to add...

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AstraZeneca’s Truqap edges closer to prostate cancer label expansion with...

After recently discontinuing R&D for Truqap in triple-negative breast cancer, AstraZeneca has some good news on its kinase inhibitor in a different indication. The UK drugmaker said Truqap...

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ADC biotech Adcendo nabs $135M Series B as it enters the clinic

Danish biotech Adcendo is joining the antibody-drug conjugate megaround train. Adcendo has corralled a $135 million Series B led by TCGX. And according to an Endpoints News tally, of the 88 biotech...

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Gilead buys experimental HIV vaccines from a small Barcelona biotech

Long known for its HIV drugs, Gilead is further delving into the field by acquiring investigational vaccines for the stubborn virus from a little-known biotech in Spain. Gilead is paying an undisclosed...

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Replimune aims to raise $125M; Otsuka makes another deal with Ionis

Plus, news about Kanglin Biotechnology, Seelos, Orbus and Sonata: Replimune’s $125M offering: The biotech announced the offering four days after it submitted an FDA application for RP1 ...

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Biohaven's myostatin inhibitor misses primary endpoint in spinal muscular...

Biohaven’s stock fell in premarket trading on Monday after it announced a Phase 3 trial failure of its myostatin inhibitor in spinal muscular atrophy and obesity. The RESILIENT study did not ...

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Cassava shares plunge as controversial Alzheimer’s drug fails Phase 3 trial

Is this the end for Cassava Sciences? After a problematic development path riddled with allegations of misleading investors, the biotech’s Alzheimer’s drug flopped on all endpoints in a Phase 3 study....

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#ASH24: Incyte touts Monjuvi data from Phase 3 follicular lymphoma trial as...

Incyte’s monoclonal antibody Monjuvi reduced certain follicular lymphoma patients’ risk of progression, relapse or death by 57% compared to placebo, the company announced Monday. The Phase 3 data,...

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Merck halts Phase 3 trial with PAH drug Winrevair following positive interim...

Merck is stopping a Phase 3 trial of its pulmonary arterial hypertension treatment Winrevair almost a year early following positive interim data, the company announced Monday. The trial, which was...

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Minnesota 340B revenue driven by hospitals and high-priced drugs, first state...

As the federal drug discount program known as 340B has seen rapid growth in recent years, Minnesota's Department of Health is looking to shine a light on where that growth is occurring. The first year ...

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Trump team asked Covid vaccine leader about heading NIH

The transition team for President-elect Donald Trump was still searching for its next National Institutes of Health director as recently as last week, multiple sources told Endpoints News, potentially...

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Bristol Myers reveals more job cuts in New Jersey

Bristol Myers Squibb's cost-cutting initiative will lead to additional layoffs in Lawrenceville, NJ, the company revealed this month in a state WARN notice. A total of 197 cuts, some of which ...

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